![]() ![]() ![]() There are many medications that can affect the INR, and even a change in diet can result in changes to the INR – either raising or lowering it. The result needs to be taken in context of recent INR measurements and dose changes. An INR result higher than the desired range means the blood is “too thin”. The Prothrombin time of a normal sample of bloodĪ result of 1.0, up to 1.5, is therefore normal.Ī low INR result means your blood is ‘not thin enough’ or coagulates too easily and puts you at risk of developing a blood clot.Ī high INR result means your blood coagulates too slowly and you risk bleeding.Īn INR lower than the desired range means the blood is “not thin enough” or clots too easily.It is important that the tube is filled to the correct level, otherwise false results may occur. The INR test is a blood test and requires a small tube of blood from a vein – approximately 4 millilitres. Artificial heart valves of the mechanical type – because of the risk of a clot forming on the valve and causing a blockage in the heart.Some cases of Heart failure (Left Ventricular, and Congestive Cardiac Failure), especially when the heart is enlarged as in some forms of cardiomyopathy.Atrial Fibrillation (AF) – an irregular heartbeat, sometimes accompanied by an enlarged left atrium – both of which predispose to the formation of blood clots in the heart, which may embolise to the blood vessels of the brain causing a cerebral infarction, a stroke – also known as a CerebroVascular Accident (CVA).Pulmonary Embolism (PE) – a clot in the lung, that has travelled through the veins (“embolised”) from a DVT formed elsewhere, such as the deep veins of the leg or pelvis. ![]() Deep Vein Thrombosis (DVT) – a clot in a deep vein, commonly of the leg.In relation to liver function tests – liver dysfunction can lead to decreased production of certain clotting factors.Monitoring as a part of warfarin therapy.The INR is calculated from prothrombin time. Destruction of the liver, caused by, e.g., cirrhosis.The most common reasons for an INR test are: Because the PT range varies and there needs to be a standard way of reporting this level, especially for the patient taking Warfarin (because this medication’s dosage is calculated based on this result), the International Normalized Ratio (INR) is used.Depletion/insufficient intake of vitamin K and.Disseminated intravascular coagulation (DIC).Inherited or acquired disease that causes the deficiency of one of the clotting factors (I, II, V, VII, X).INR 3.0 - the INR is too high and may pose the risk of excessive bleeding❗This level of INR might be recommended for people who have the older generation of artificial heart valve. ![]()
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